AdeC

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  • Description: adenine deaminase

Gene name adeC
Synonyms ade, yzaD
Essential no
Product adenine deaminase
Function utilization of adenine as nitrogen source,
purine salvage and interconversion
Gene expression levels in SubtiExpress: adeC
Metabolic function and regulation of this protein in SubtiPathways:
Purine salvage, Purine catabolism
MW, pI 62 kDa, 4.724
Gene length, protein length 1731 bp, 577 aa
Immediate neighbours ktrC, rnjA
Sequences Protein DNA Advanced_DNA
Genetic context
AdeC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AdeC expression.png




























Categories containing this gene/protein

utilization of nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14520

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Adenine + H2O = hypoxanthine + NH3 (according to Swiss-Prot)
  • Protein family: adenine deaminase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

P Nygaard, P Duckert, H H Saxild
Role of adenine deaminase in purine salvage and nitrogen metabolism and characterization of the ade gene in Bacillus subtilis.
J. Bacteriol.: 1996, 178(3);846-53
[PubMed:8550522] [WorldCat.org] [DOI] (P p)