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  • Description: acyl-CoA dehydrogenase <br/><br/>
Gene name acdA
Essential no
Product acyl-CoA dehydrogenase
Function fatty acid degradation
Metabolic function and regulation of this protein in SubtiPathways: <br/>Fatty acid degradation
MW, pI 41 kDa, 4.951
Gene length, protein length 1137 bp, 379 aa
Immediate neighbours rpoE, fadF
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> AcdA context.gif
<div align="right"> <small>This image was kindly provided by SubtiList</small></div>


The gene

Basic information

  • Locus tag: BSU37170

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF (according to Swiss-Prot)
  • Protein family: acyl-CoA dehydrogenase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2Z1Q (from Thermus thermophilus hb8, 40% identity, 55% similarity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the absence of long-chain fatty acids (FadR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks