ABC transporters

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transport proteins


Importers

Uptake of carbon sources

ATPase subunit of multiple sugar transport systems

Uptake of amino acids

Uptake of nucleosides

Uptake of peptides

Uptake of compatible solutes for osmoprotection

Uptake of cofactors

Uptake of iron/ siderophores

Uptake of ions

ABC transporters of unknown function

Exporters

Efflux of antibiotics

  • VmlR: efflux of virginiamycin M and lincomycin
  • BmrA: efflux of multiple antibiotics
  • BmrC-BmrD: efflux of multiple antibiotics
  • YfiL-YfiM-YfiN: probably efflux of linearmcin

Export of antibiotic substances

Export of peptides

Export of cell wall components

Export of ions

Exporters of unknown function

Regulatory ABC transporters

Relevant publications

Christoph Thomas, Robert Tampé
Structural and Mechanistic Principles of ABC Transporters.
Annu Rev Biochem: 2020, 89;605-636
[PubMed:32569521] [WorldCat.org] [DOI] (I p)

Kaspar P Locher
Mechanistic diversity in ATP-binding cassette (ABC) transporters.
Nat Struct Mol Biol: 2016, 23(6);487-93
[PubMed:27273632] [WorldCat.org] [DOI] (I p)

Susanne Gebhard
ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation.
Mol Microbiol: 2012, 86(6);1295-317
[PubMed:23106164] [WorldCat.org] [DOI] (I p)

Sebastian Dintner, Anna Staron, Evi Berchtold, Tobias Petri, Thorsten Mascher, Susanne Gebhard
Coevolution of ABC transporters and two-component regulatory systems as resistance modules against antimicrobial peptides in Firmicutes Bacteria.
J Bacteriol: 2011, 193(15);3851-62
[PubMed:21665979] [WorldCat.org] [DOI] (I p)

Thomas Eitinger, Dmitry A Rodionov, Mathias Grote, Erwin Schneider
Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions.
FEMS Microbiol Rev: 2011, 35(1);3-67
[PubMed:20497229] [WorldCat.org] [DOI] (I p)

Amy L Davidson, Elie Dassa, Cedric Orelle, Jue Chen
Structure, function, and evolution of bacterial ATP-binding cassette systems.
Microbiol Mol Biol Rev: 2008, 72(2);317-64, table of contents
[PubMed:18535149] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

C F Higgins
ABC transporters: from microorganisms to man.
Annu Rev Cell Biol: 1992, 8;67-113
[PubMed:1282354] [WorldCat.org] [DOI] (P p)


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