yycB

168

similar to permeases

locus: BSU_40480

Molecular weight: 43.02 kDa

pI: 10.5

Protein length: 402 aa

Gene length: 1209 bp

function: unknown

product: unknown

essential: no

synonyms: yycB

List of homologs in different organisms, belongs to COG2807 (Galperin et al., 2021)

Gene

Coordinates: 4,159,790  4,160,998

Advertisement

The protein

Protein family

• [wiki|major facilitator superfamily] (according to UniProt)

Structure

• [AF|P37482]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|1CB229DE87D56674903A8348657FA3B3117FEADD|yycC]-[gene|00F319EEC8420F859BA2657B9D4D1281853A94BD|yycB]

  description: [Pubmed|12823818]

  regulation

  • repressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|12823818]

  regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA]: repression, [Pubmed|12823818], in [regulon|protein:857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA regulon]

• genes: [gene|1CB229DE87D56674903A8348657FA3B3117FEADD|yycC]-[gene|00F319EEC8420F859BA2657B9D4D1281853A94BD|yycB]-[gene|CFEA05E10517C00222126F959A1D2DCE7604E478|yycA]

  description: [Pubmed|22383849]

  regulation

  • repressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA]) [Pubmed|12823818]

  regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA]: repression, [Pubmed|12823818], in [regulon|protein:857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|tnrA regulon]

Biological materials

Mutant

• MGNA-B832 (yycB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1831 NBRP B. subtilis, Japan]
• BKE40480 ([gene|00F319EEC8420F859BA2657B9D4D1281853A94BD|yycB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE40480 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAGCAGTTACTCCTCTTT,  downstream forward: _UP4_TAAAGCGGGGAAGATATCTC
• BKK40480 ([gene|00F319EEC8420F859BA2657B9D4D1281853A94BD|yycB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK40480 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAAGCAGTTACTCCTCTTT,  downstream forward: _UP4_TAAAGCGGGGAAGATATCTC

References

• 12823818,25755103