yxlD

168

negative regulation of [protein|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]-directed transcription of the [gene|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY] operon

locus: BSU_38680

Molecular weight: 7.71 kDa

pI: 10.27

Protein length: 68 aa

Gene length: 207 bp

function: negative regulation of [protein|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]-directed transcription of the [gene|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY] operon

product: unknown

essential: no

synonyms: yxlD

List of homologs in different organisms

Gene

Coordinates: 3,969,796 → 3,970,002

Phenotypes of a mutant

• the mutant tends to acquire suppressor mutations that result in improved growth [Pubmed|28189581]

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The protein

Structure

• [AF|P94372]

Expression and Regulation

Operons

• genes: [gene|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]-[gene|C07156CBA0AA3BAB24D17D15708FC68E74A854A7|yxlC]-[gene|CAADFAFD4C39362D0D0F242C926AE101C683EB5D|yxlD]-[gene|B40D01DDD9EF8B64E46CA7DBF4BAC3DBF8A73986|yxlE]-[gene|D246F61BEAE0D3D6707B4C43A634C02876CC5395|yxlF]-[gene|DCC03844AC58A198B851B564D0A6459C39EBDA2F|yxlG]

  description: [Pubmed|14769884]

  sigma factors

  • [protein|801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY]: sigma factor, [Pubmed|12897008], in [regulon|protein:801E92306971E26AD4AB155172B7F4EFDE2F9170|sigY regulon]

additional information

• the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]

Biological materials

Mutant

• MGNA-B759 (yxlD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1758 NBRP B. subtilis, Japan]
• BKE38680 (Δ[gene|CAADFAFD4C39362D0D0F242C926AE101C683EB5D|yxlD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38680 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGTCATCCGCGTTTCACCTC,  downstream forward: _UP4_CAATGAATATTTCTTGGGAA
• BKK38680 (Δ[gene|CAADFAFD4C39362D0D0F242C926AE101C683EB5D|yxlD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38680 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TGTCATCCGCGTTTCACCTC,  downstream forward: _UP4_CAATGAATATTTCTTGGGAA

References

• 14769884,12897008,26883633