yutK

168

similar to Na⁺/nucleoside cotransporter

locus: BSU_32180

Molecular weight: 42.12 kDa

pI: 9.48

Protein length: 404 aa

Gene length: 1215 bp

function: unknown

product: unknown

essential: no

synonyms: yutK

List of homologs in different organisms, belongs to COG1972 (Galperin et al., 2021)

Gene

Coordinates: 3,307,017  3,308,231

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The protein

Protein family

• concentrative nucleoside transporter (CNT) (TC 2.A.41) family (with [protein|4F718681A7AD0C86B2551248570F493AC0B2E7E9|nupC] and [protein|C333F405F597FF260FFA0EC616B8CF6BF454815B|nupG], according to UniProt)

Structure

• [PDB|3TIJ] (from Vibrio cholerae, 54% identity) [pubmed|22407322]
• [AF|O32115]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6|yutK]

  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A970 (yutK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/970 NBRP B. subtilis, Japan]
• BKE32180 ([gene|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6|yutK]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32180 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAATACTCGTACACCTC,  downstream forward: _UP4_TAAACGATAAAAGCTCCTTG
• BKK32180 ([gene|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6|yutK]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32180 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGAATACTCGTACACCTC,  downstream forward: _UP4_TAAACGATAAAAGCTCCTTG

References

• 20525796,22407322