ccrZ

ccrZ
168

activator of [protein|6740108089F13116F200C15F35C2E7561E990FEB|dnaA]-dependent initiation of [category|SW.3.1.1|DNA replication]

locus
BSU_29920
Molecular weight
30.64 kDa
pI
5.81
Protein length
Gene length
function
control of [category|SW.3.1.1|DNA replication]
product
activator of [protein|6740108089F13116F200C15F35C2E7561E990FEB|dnaA]-dependent initiation of [category|SW.3.1.1|DNA replication]
essential
no
synonyms
ytmP

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0510 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,060,674  3,061,288
Phenotypes of a mutant
sensitive to DNA damage [pubmed|35576203]
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The protein
Protein family
aminoglycoside phosphotransferase family (with [protein|349C99C258331962455100E2662DA2272E946C8A|ycbJ], according to UniProt)
Structure
[PDB|7S3L] [pubmed|35576203]
[PDB|4R77] (from Streptococcus pneumoniae, 27% identity) [pubmed|25781969]
[AF|C0SPC1]
Expression and Regulation
Operons
genes
[gene|651F41AA16B0BB59A613D74302F441BF6D5BFF64|ccrZ]
description
[Pubmed|22383849]
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[gene|651F41AA16B0BB59A613D74302F441BF6D5BFF64|ccrZ]

2024-03-20 08:46:51

Jstuelk

45

9535d46f690363b8fe1b0be4ceb913c52f3223c5

DD6A6BE3B43C0EA9B2C8965E35EE18EB5B0BB804

Biological materials
Mutant
MGNA-A434 (ytmP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/434 NBRP B. subtilis, Japan]
BKE29920 ([gene|651F41AA16B0BB59A613D74302F441BF6D5BFF64|ccrZ]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCGTTTTGTCCAAACCA,  downstream forward: _UP4_CTCATGAAACGAATTGTTGA
BKK29920 ([gene|651F41AA16B0BB59A613D74302F441BF6D5BFF64|ccrZ]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCGTTTTGTCCAAACCA,  downstream forward: _UP4_CTCATGAAACGAATTGTTGA
References
Research papers
25781969,34373624,35576203,36053906

651F41AA16B0BB59A613D74302F441BF6D5BFF64

Page visits: 8239

Time of last update: 2024-03-28 14:53:35

Author of last update: Jstuelk