ysnA

ysnA
168

ITPase

locus
BSU_28360
Molecular weight
21.79 kDa
pI
4.95
Protein length
Gene length
function
purine metabolism
product
ITPase
essential
no
ec
3.6.1.15
synonyms
ysnA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0127 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,900,545  2,901,141
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The protein
Catalyzed reaction/ biological activity
H2O + XTP --> diphosphate + H+ + XMP (according to UniProt)
dITP + H2O --> dIMP + diphosphate + H+ (according to UniProt)
H2O + ITP --> diphosphate + H+ + IMP (according to UniProt)
Protein family
HAM1 NTPase family (single member, according to UniProt)
Structure
[PDB|2MJP] (from ''Methanococcus jannaschii'') [Pubmed|10404228], [PDB|4BNQ] (from E. Coli 52% identity)
[AF|P94558]
Expression and Regulation
Operons
genes
[gene|A18474CD50C2A1A83CF04C74098659BF1649B4DC|rph]-[gene|1BE734901DACBB56AB688C776F0AF8D298462518|ysnA]-[gene|13DF13F1EA21BC78035E5ED8B7AF2320235284A6|ysnB]
description
[Pubmed|22383849]
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[gene|A18474CD50C2A1A83CF04C74098659BF1649B4DC|rph]→[gene|13DF13F1EA21BC78035E5ED8B7AF2320235284A6|ysnB]

2024-03-06 10:00:56

Jstuelk

35

0f9e962c8f46d37722865610c6c0a69f06780cd3

B6C3C0619B9997D38F45FCD64F603B8C04463A79

Biological materials
Mutant
MGNA-B030 (ysnA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1029 NBRP B. subtilis, Japan]
BKE28360 ([gene|1BE734901DACBB56AB688C776F0AF8D298462518|ysnA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE28360 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGCCTTTCTGTCTTTATT,  downstream forward: _UP4_GAGGCATAAGGAGGAAGCTT
BKK28360 ([gene|1BE734901DACBB56AB688C776F0AF8D298462518|ysnA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK28360 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAGCCTTTCTGTCTTTATT,  downstream forward: _UP4_GAGGCATAAGGAGGAAGCTT
References
10404228,11278832

1BE734901DACBB56AB688C776F0AF8D298462518

Page visits: 1721

Time of last update: 2024-03-27 19:09:55

Author of last update: Melvin.boenninger