yrzF

168

putative serine/threonine-protein kinase

locus: BSU_27785

Molecular weight: 25.00 kDa

pI: 9.185

Protein length: 215 aa

Gene length: 648 bp

function: unknown

product: unknown

essential: no

synonyms: yrzF

List of homologs in different organisms, belongs to COG2112 (Galperin et al., 2021)

Gene

Coordinates: 2,840,110 → 2,840,757

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The protein

Catalyzed reaction/ biological activity

• ATP + L-seryl-[protein] --> ADP + H⁺ + O-phospho-L-seryl-[protein] (according to UniProt)
• ATP + L-threonyl-[protein] --> ADP + H⁺ + O-phospho-L-threonyl-[protein] (according to UniProt)

Protein family

• [wiki|protein kinase superfamily] (according to UniProt)
• [wiki|Ser/Thr protein kinase family] (according to UniProt)

[wiki|Domains]

• [wiki|Protein kinase domain] (aa 27-215) (according to UniProt)

Structure

• [AF|O32057]

Expression and Regulation

Operons

• genes: [gene|DDE33287BF9752489B40BA8EF5138D6CC4B0415E|yrzF]

  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-B521 (yrzF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1520 NBRP B. subtilis, Japan]
• BKE27785 (Δ[gene|DDE33287BF9752489B40BA8EF5138D6CC4B0415E|yrzF]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27785 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCATTCACCTTCTTTG,  downstream forward: _UP4_TAAATCAAAAAGGCAGCCGC
• BKK27785 (Δ[gene|DDE33287BF9752489B40BA8EF5138D6CC4B0415E|yrzF]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27785 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTCATTCACCTTCTTTG,  downstream forward: _UP4_TAAATCAAAAAGGCAGCCGC