yqxC
168
similar to rRNA methyltransferase
locus
BSU_24260
Molecular weight
29.50 kDa
pI
10.11
function
unknown
product
putative rRNA methyltransferase
essential
no
synonyms
yqxC, yqiF
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1189 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,522,871 2,523,716
The protein
Protein family
[wiki|S4 RNA-binding domain] superfamily (according to http://www.ebi.ac.uk/interpro/entry/IPR036986 Interpro)
TlyA family (single member, according to UniProt)
[wiki|Domains]
[wiki|S4 RNA-binding domain] (aa 6-67) (according to UniProt)
[wiki|Cofactors]
SAM [pubmed|28031456]
Structure
[PDB|3HP7] (from Streptococcus thermophilus, 60% identity)
[AF|P19672]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]
description
[Pubmed|2507400]
additional information
the terminator is [protein|search|NusA]-dependent [ http://www.nature.com/articles/nmicrobiol20157 Reference]
genes
[gene|EA9FCF84AE4FA80993566B62A9200D4B32AF5670|dxs]-[gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]-[gene|62F8E0D6BC9DA6390256FA8FB684EA5C9C722AE4|ahrC]-[gene|5680A06A74D3EC6310EF8677795511C75DB3059E|recN]
description
[pubmed|22383849]
regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
regulatory mechanism
stringent response: negative regulation, [pubmed|11948165], in [regulon|other_regulator:stringent response|stringent response]
Biological materials
Mutant
MGNA-C369 (yqxC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2367 NBRP B. subtilis, Japan]
BKE24260 ([gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE24260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCTAATCGTTCTTTCTTTG, downstream forward: _UP4_TAATAGGGCGCTATTATTCC
BKK24260 ([gene|923C4177500E9678A0B4855F8F481D4A36ECD863|yqxC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK24260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCTAATCGTTCTTTCTTTG, downstream forward: _UP4_TAATAGGGCGCTATTATTCC
References
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Time of last update: 2024-04-19 15:09:05
Author of last update: Jstuelk