yodL

168

modulator of [protein|A4C8719E06F774A6EB4D79757CC79CF89E453A54|mreB] activity

locus: BSU_19640

Molecular weight: 12.05 kDa

pI: 9.88

Protein length: 105 aa

Gene length: 315 bp

function: control of [wiki|cell division]

product: modulator of [protein|A4C8719E06F774A6EB4D79757CC79CF89E453A54|mreB] activity

essential: no

synonyms: yodL

List of homologs in different organisms

Gene

Coordinates: 2,136,538 → 2,136,852

Phenotypes of a mutant

• overexpression results in loss of cell width and cell lysis (suppressed by mutations in [protein|A4C8719E06F774A6EB4D79757CC79CF89E453A54|mreB] that affect the interaction surface for [protein|6071A84EF190C820DB8985C08ABC74F744B793DB|rodZ]) [Pubmed|27215790]

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The protein

Structure

• [AF|O30472]

Expression and Regulation

Operons

• genes: [gene|1EF303EA929237C2BD7A4507AFB248B800517B9F|yodL]

  description: [Pubmed|22383849]

  regulation

  • expressed early during [wiki|sporulation] ([wiki|Spo0A]) [Pubmed|27215790]

  regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A]: activation, [Pubmed|27215790], in [regulon|protein:2C54FE2ADC82FF414D732018C90649D477A925AD|spo0A regulon]

Biological materials

Mutant

• MGNA-B440 (yodL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1439 NBRP B. subtilis, Japan]
• BKE19640 (Δ[gene|1EF303EA929237C2BD7A4507AFB248B800517B9F|yodL]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE19640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAAGATCCCCTCCCTTT,  downstream forward: _UP4_TAATGAAAAGAAAACTGCGG
• BKK19640 (Δ[gene|1EF303EA929237C2BD7A4507AFB248B800517B9F|yodL]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK19640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAAGATCCCCTCCCTTT,  downstream forward: _UP4_TAATGAAAAGAAAACTGCGG

References

• 27215790,22383849