ykoG

ykoG
168

two-component response regulator ([wiki|OmpR family])

locus
BSU_13250
Molecular weight
25.86 kDa
pI
5.11
Protein length
Gene length
function
unknown
product
two-component response regulator ([wiki|OmpR family])
essential
no
synonyms
ykoG

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0745 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,391,953  1,392,639
Visit Sartorius.com Visit Sartorius.com
Advertisement
The protein
Protein family
[wiki|OmpR family] of two-component response regulators
[wiki|Domains]
[wiki|Response regulatory domain] (aa 5-119) (according to UniProt)
Structure
[PDB|5ED4] (from Mycobacterium tuberculosis, 44% identity) [pubmed|27079268]
[AF|O34903]
Modification
phosphorylated by [protein|9E8A6AB3920BFBFDAAD1F2E4F333A32354ABB25B|ykoH] on an Asp residue
Effectors of protein activity
phosphorylation likely affects DNA-binding activity
Paralogous protein(s)
[protein|706983E6942E883D3A9D45693E7B4015AEABE60B|yclJ], [protein|7F340423A34CE40D1F1AA8D373F7C4B859A6496D|walR], [protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|phoP]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|6A37531896205A9B894C81AB0563C216C0B52CD7|ykoG]-[gene|9E8A6AB3920BFBFDAAD1F2E4F333A32354ABB25B|ykoH]-[gene|0678357183072D2716B913C07103CEBF65E60D14|ykoI]-[gene|348EAFC260435B3E0ED3CC7BC27EBA8DCFCBBEDC|ykoJ]
description
[Pubmed|22383849]
Open in new tab

[gene|6A37531896205A9B894C81AB0563C216C0B52CD7|ykoG]→[gene|348EAFC260435B3E0ED3CC7BC27EBA8DCFCBBEDC|ykoJ]

2024-03-22 16:06:53

Jstuelk

37

94c4f5ed861eb90d409ae60d8f15a7e83defa9a9

4CE73C876804A253735805E36E7F7CBF728FACD6

Biological materials
Mutant
MGNA-A775 (ykoG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/775 NBRP B. subtilis, Japan]
BKE13250 ([gene|6A37531896205A9B894C81AB0563C216C0B52CD7|ykoG]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE13250 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAATTTGACCATCCTCTCC,  downstream forward: _UP4_GGCTATGCCATTAAGGGGTA
BKK13250 ([gene|6A37531896205A9B894C81AB0563C216C0B52CD7|ykoG]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK13250 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAATTTGACCATCCTCTCC,  downstream forward: _UP4_GGCTATGCCATTAAGGGGTA
References
10094672,23504016,27079268

6A37531896205A9B894C81AB0563C216C0B52CD7

Page visits: 1793

Time of last update: 2024-03-28 22:51:58

Author of last update: Melvin.boenninger