yisX

yisX
168

binds to DNA lesions, may be involved in DNA damage repair

locus
BSU_10890
Molecular weight
23.58 kDa
pI
5.05
Protein length
Gene length
function
unknown
product
unknown
essential
no
ec
null
synonyms
yisX

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1357 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,168,199  1,168,837
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The protein
Catalyzed reaction/ biological activity
binds to 8-oxoG and RNA base DNA lesions [pubmed|37250769]
[wiki|Domains]
3 Pentapeptide repeat domains (aa 63-102, aa 103-142, aa 143-182) (according to UniProt)
Structure
[PDB|6FLS] (from Clostridium botulinum, corresponds to aa 28 ... 235, 24% identity) [pubmed|30539762]
[AF|O06733]
Expression and Regulation
Operons
genes
[gene|5237C86931876179C9CE67A9B04A0A62ADA7C25C|yisX]
description
[pubmed|22383849]
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[gene|5237C86931876179C9CE67A9B04A0A62ADA7C25C|yisX]

2024-02-27 06:58:53

Jstuelk

29

5f796c5892499f98750580b17780679dae3ca474

1B56988078C6BD83EC14967F5C4A8880DC0014F5

Biological materials
Mutant
MGNA-B193 (yisX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1192 NBRP B. subtilis, Japan]
BKE10890 ([gene|5237C86931876179C9CE67A9B04A0A62ADA7C25C|yisX]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10890 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTGATGACATCCTTTGC,  downstream forward: _UP4_GGAGCTGTCATCGTATAACC
BKK10890 ([gene|5237C86931876179C9CE67A9B04A0A62ADA7C25C|yisX]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10890 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGTGATGACATCCTTTGC,  downstream forward: _UP4_GGAGCTGTCATCGTATAACC
References
Research papers
30539762,37250769

5237C86931876179C9CE67A9B04A0A62ADA7C25C

Page visits: 1346

Time of last update: 2024-03-28 06:41:32

Author of last update: Jstuelk