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  • Description: similar to metalloprotease

Gene name yhfN
Synonyms yzoA
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yhfN
MW, pI 48 kDa, 6.077
Gene length, protein length 1278 bp, 426 aa
Immediate neighbours yhfM, aprE
Sequences Protein DNA DNA_with_flanks
Genetic context
YhfN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YhfN expression.png


Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10290

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M48B family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: yhfN (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


K Fujimura-Kamada, F J Nouvet, S Michaelis
A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor.
J. Cell Biol.: 1997, 136(2);271-85
[PubMed:9015299] [WorldCat.org] (P p)

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