yhcS

yhcS
168

sortase

locus
BSU_09200
Molecular weight
21.83 kDa
pI
7.17
Protein length
Gene length
function
anchoring of proteins to the cell wall
product
sortase
essential
no
synonyms
yhcS

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3764 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
994,998  995,594
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The protein
Catalyzed reaction/ biological activity
C-terminal anchoring of proteins to the cell wall
Protein family
bacterial sortase family (with [protein|B17670494CC6F7C1138F4B4ECC0FEE8FC15609A2|ywpE], according to UniProt)
Structure
[PDB|2LN7] (B. anthracis SrtD, corresponds to aa 69 - 195 of YhcS, 44% identity) [pubmed|22974341]
[AF|P54603]
[wiki|Localization]
membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|DAFBC470DA0FA437B117716DE899A8D3EC454672|yhcR]-[gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]
description
[pubmed|22383849]
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[gene|DAFBC470DA0FA437B117716DE899A8D3EC454672|yhcR]→[gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]

2024-01-25 01:55:27

Jstuelk

42

c7c6b994028ef6bf640ec148924c4dc6e1d65947

3FEED70D10CEC51F0EFA887B598D1BC1D3BC6380

Biological materials
Mutant
MGNA-A661 (yhcS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/661 NBRP B. subtilis, Japan]
BKE09200 ([gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09200 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GATGAATAGTGGAATAACTT,  downstream forward: _UP4_TAAAAAGCCGAGGCAGTGCC
BKK09200 ([gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09200 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GATGAATAGTGGAATAACTT,  downstream forward: _UP4_TAAAAAGCCGAGGCAGTGCC
References
Reviews
22026821,25845800
Original Publications
21800427,21906378,22020651,22974341

A24243129860F1B043EBE1358FAEA57BED111BBC

Page visits: 1875

Time of last update: 2024-03-28 13:23:50

Author of last update: Melvin.boenninger