tlp

168

thioredoxin-like protein

locus: BSU_18030

Molecular weight: 9.58 kDa

pI: 4.44

Protein length: 83 aa

Gene length: 252 bp

function: unknown

product: thioredoxin-like protein

essential: no

synonyms: tlp

List of homologs in different organisms, belongs to COG5863 (Galperin et al., 2021)

Gene

Coordinates: 1,930,447 → 1,930,698

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The protein

Protein family

• tlp family (single member, according to UniProt)

Structure

• [AF|Q45060]

[wiki|Localization]

• spore core (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|5D79D9D38B588FE0EC688D54FE68E6F49238DA46|sspN]-[gene|DE52E15D900F9665E35D2C8138DA3ABFC2B7B723|tlp]

  description: [Pubmed|10333516]

  regulation

  • expressed during sporulation in the forespore ([protein|search|SigF], [protein|search|SigG]) [Pubmed|15699190,10333516]

  sigma factors

  • [protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|15699190,10333516], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|15699190,10333516], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]

additional information

• the mRNA belongs to the 46 most abundant mRNA species in dormant spores [pubmed|30782632]

Biological materials

Mutant

• BKE18030 (Δ[gene|DE52E15D900F9665E35D2C8138DA3ABFC2B7B723|tlp]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE18030 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCGGATGTACCTCCTAG,  downstream forward: _UP4_TAAAAAACCAGGGAAACCTG
• BKK18030 (Δ[gene|DE52E15D900F9665E35D2C8138DA3ABFC2B7B723|tlp]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK18030 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCGGATGTACCTCCTAG,  downstream forward: _UP4_TAAAAAACCAGGGAAACCTG

References

Reviews

• 35638784

Original Publications

• 16497325,15699190,10333516,30782632