scr

scr
168

4.5 S RNA, causes RNA-driven elongation arrest by interaction with the 23S rRNA

locus
BSU_misc_RNA_2
function
presecretory protein translocation
product
small cytoplasmic RNA (scRNA, 4.5S RNA)
essential
yes
synonyms
scr

Genomic Context

Categories containing this gene/protein

This gene is a member of the following regulons

Gene
Coordinates
26,533 → 26,635
Phenotypes of a mutant
the gene is essential [Pubmed|7506707]
RNA
Structure
[PDB|4UE4] (complex [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[protein|097C817A5A3E31F73F6ABC4AA95852A64E43A057|scr] RNA) [Pubmed|26344568]
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The protein
Structure
[PDB|4UE4] (complex [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]-[protein|097C817A5A3E31F73F6ABC4AA95852A64E43A057|scr] RNA) [Pubmed|26344568]
Expression and Regulation
Operons
genes
[gene|5FC8D0B30B55C1CBC2CDE8E56E7E948A781EF2AB|yaaJ]-[gene|097C817A5A3E31F73F6ABC4AA95852A64E43A057|scr]
description
null
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, (both promoters), in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|5FC8D0B30B55C1CBC2CDE8E56E7E948A781EF2AB|yaaJ]→[gene|097C817A5A3E31F73F6ABC4AA95852A64E43A057|scr]

2024-03-05 02:12:23

ghost

78

b2d28cf402e740ffdb8d72c8cd99dd7c5f187533

7A6D368CD211CDB194D1980F4321F881B55AD15E

additional information
the mature 5' end of RNA is generated by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III]-mediated cleavage at 38 nts [pubmed|26883633]
the mature 3' end of RNA is generated by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y]-mediated cleavage at 320 nts, and further trimming to 308 nts [pubmed|25402410]
labs
[wiki|David Bechhofer], Mount Sinai School, New York, USA
References
Reviews
25212246,27890920
Original Publications
9346318,2468993,17576666,1372600,7506707,1383945,7538759,10224127,9677377,8662730,10222262,25270875,25402410,26883633,26344568

097C817A5A3E31F73F6ABC4AA95852A64E43A057

Page visits: 3081

Time of last update: 2024-03-29 06:42:08

Author of last update: Jstuelk