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  • Description: subtilosin A

Gene name sboA
Synonyms sbo
Essential no
Product subtilosin A
Function antimicrobial peptide
Gene expression levels in SubtiExpress: sboA
MW, pI 4 kDa, 4.569
Gene length, protein length 129 bp, 43 aa
Immediate neighbours ywiB, sboX
Sequences Protein DNA DNA_with_flanks
Genetic context
SboA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SboA expression.png


Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon, ResD regulon, Rok regulon

The gene

Basic information

  • Locus tag: BSU37350

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacteriocin class V family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Additional publications: PubMed

Mark A Strauch, Benjamin G Bobay, John Cavanagh, Fude Yao, Angelo Wilson, Yoann Le Breton
Abh and AbrB control of Bacillus subtilis antimicrobial gene expression.
J. Bacteriol.: 2007, 189(21);7720-32
[PubMed:17720793] [] [DOI] (P p)

Mark Albano, Wiep Klaas Smits, Linh T Y Ho, Barbara Kraigher, Ines Mandic-Mulec, Oscar P Kuipers, David Dubnau
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions.
J. Bacteriol.: 2005, 187(6);2010-9
[PubMed:15743949] [] [DOI] (P p)

M M Nakano, G Zheng, P Zuber
Dual control of sbo-alb operon expression by the Spo0 and ResDE systems of signal transduction under anaerobic conditions in Bacillus subtilis.
J. Bacteriol.: 2000, 182(11);3274-7
[PubMed:10809710] [] (P p)

G Zheng, R Hehn, P Zuber
Mutational analysis of the sbo-alb locus of Bacillus subtilis: identification of genes required for subtilosin production and immunity.
J. Bacteriol.: 2000, 182(11);3266-73
[PubMed:10809709] [] (P p)

G Zheng, L Z Yan, J C Vederas, P Zuber
Genes of the sbo-alb locus of Bacillus subtilis are required for production of the antilisterial bacteriocin subtilosin.
J. Bacteriol.: 1999, 181(23);7346-55
[PubMed:10572140] [] (P p)

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