rhaA

rhaA
168

L-rhamnose isomerase

locus
BSU_31180
Molecular weight
48.48 kDa
pI
5.35
Protein length
Gene length
function
rhamnose utilization
product
L-rhamnose isomerase
essential
no
ec
5.3.1.14
synonyms
rhaA, yulE

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4806 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,197,933 → 3,199,207
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The protein
Catalyzed reaction/ biological activity
L-rhamnose = L-rhamnulose [Pubmed|26712933]
Protein family
rhamnose isomerase family (single member, according to UniProt)
Structure
[PDB|3P14] (from B. halodurans, 78% identity) [pubmed|24925069]
[AF|O05264]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|C32AE30BF7931D6171E9DE75C67504F81DD0F227|rhaEW]-[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]-[gene|693040A5BA7A25AD485B7B28DBD6E8AAC77450F7|rhaB]-[gene|294C0CC675088B2A2EEFC26FAF1A628002B82C59|rhaM]-[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]
description
[Pubmed|26712933,22383849]
regulation
expression during spore [wiki|germination] is increased under conditions of osmotic stress [Pubmed|27766092]
regulatory mechanism
[protein|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]: repression, [Pubmed|26712933], in [regulon|protein:F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|26712933], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|26712933], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Open in new tab

[gene|C32AE30BF7931D6171E9DE75C67504F81DD0F227|rhaEW]→[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]

2024-03-10 08:59:34

ghost

65

19fb437091a8b0a4c85dca603a6b54dd43243683

2050B8CB3997650C17442F14F1C06F783D5E7647

genes
[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]-[gene|693040A5BA7A25AD485B7B28DBD6E8AAC77450F7|rhaB]-[gene|294C0CC675088B2A2EEFC26FAF1A628002B82C59|rhaM]-[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]
description
[Pubmed|22383849]
regulation
expression during spore [wiki|germination] is increased under conditions of osmotic stress [Pubmed|27766092]
Open in new tab

[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]→[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]

2024-03-04 15:41:37

ghost

45

f78e9504a24134fdb2f0831248c760840f86c618

D3F58B4ED3CAB9282D2D0E5923C9CC3BE67E3819

Biological materials
Mutant
MGNA-B544 (yulE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1543 NBRP B. subtilis, Japan]
BKE31180 (Δ[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31180 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATACGGCTCTCTCCCTTTA,  downstream forward: _UP4_TAATAAAAAATCCGCCGCGG
BKK31180 (Δ[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31180 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATACGGCTCTCTCCCTTTA,  downstream forward: _UP4_TAATAAAAAATCCGCCGCGG
References
26712933,10960106,24391637,22383849,24925069

FDDC16D57752D81299CDD426257C1CD49890C89C

Page visits: 2161

Time of last update: 2024-03-28 19:23:08

Author of last update: Melvin.boenninger