nin

168

inhibitor of the DNA degrading activity of [protein|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]

locus: BSU_03420

Molecular weight: 14.86 kDa

pI: 4.92

Protein length: 132 aa

Gene length: 399 bp

function: genetic transformation, DNA uptake

product: inhibitor of the DNA degrading activity of [protein|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]

essential: no

synonyms: nin, comJ

List of homologs in different organisms

Gene

Coordinates: 371,729  372,127

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The protein

Structure

• [PDB|4MQD]
• [AF|P12669]

Modification

• phosphorylated on Arg-96 [Pubmed|22517742]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|99581CC6AFFA2D1392748B4D9C99DEF8B7601F75|nucA]-[gene|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23|nin]

  description: [Pubmed|11359569]

  regulatory mechanism

  • [protein|08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK]: activation, [Pubmed|7746143], in [regulon|protein:08CFA2C72931A75532D4289BC1D18A826DE9F9CA|comK regulon]

Biological materials

Mutant

• BKE03420 ([gene|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23|nin]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATGTGCTGTTCCTCCTCT,  downstream forward: _UP4_TAATGAAAAACCCCTGAGAG
• BKK03420 ([gene|3A54C644DD1CCA5C08CB9C5CD648D44889E68D23|nin]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATGTGCTGTTCCTCCTCT,  downstream forward: _UP4_TAATGAAAAACCCCTGAGAG

References

• 11814663,11359569,7746143,22517742