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  • Description: lipoate-protein ligase

Gene name lplJ
Synonyms yhfJ
Essential no
Product Lipoate:protein ligase
Function lipoic acid metabolism
Gene expression levels in SubtiExpress: lplJ
Metabolic function and regulation of this protein in SubtiPathways:
MW, pI 37 kDa, 5.835
Gene length, protein length 993 bp, 331 aa
Immediate neighbours yhfI, yhfK
Sequences Protein DNA DNA_with_flanks
Genetic context
YhfJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LplJ expression.png


Categories containing this gene/protein

Biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10250

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation: induced by valine PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks


Quin H Christensen, Natalia Martin, Maria C Mansilla, Diego de Mendoza, John E Cronan
A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis.
Mol. Microbiol.: 2011, 80(2);350-63
[PubMed:21338421] [] [DOI] (I p)

Natalia Martin, Quin H Christensen, María C Mansilla, John E Cronan, Diego de Mendoza
A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis.
Mol. Microbiol.: 2011, 80(2);335-49
[PubMed:21338420] [] [DOI] (I p)

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