hemE

hemE
168

uroporphyrinogen decarboxylase (uroporphyrinogen III)

locus
BSU_10120
Molecular weight
39.49 kDa
pI
5.26
Protein length
Gene length
function
heme biosynthesis
product
uroporphyrinogen decarboxylase (uroporphyrinogen III)
essential
no
ec
4.1.1.37
synonyms
hemE, uroD

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0407 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,086,117  1,087,178
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The protein
Catalyzed reaction/ biological activity
4 H+ + uroporphyrinogen III --> 4 CO2 + coproporphyrinogen III (according to UniProt)
Protein family
uroporphyrinogen decarboxylase family (single member, according to UniProt)
Structure
[PDB|2INF]
[AF|P32395]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|762E7731EFEAC9F38074D7A7E9A3E5759437CDCA|hemE]-[gene|E4C588EC93132CCBE4F40559F8A480A66A2D82D7|hemH]-[gene|7541AD7D06BC4CE30AD576562E0053CC1E25B4D6|hemY]
description
[Pubmed|1459957]
Open in new tab

[gene|762E7731EFEAC9F38074D7A7E9A3E5759437CDCA|hemE]→[gene|7541AD7D06BC4CE30AD576562E0053CC1E25B4D6|hemY]

2024-03-23 18:15:32

ghost

73

cc3badb89ccb30b0e5bcbdd78cda19adf9729720

53F55E33273DE40E70DE56EF56FA66E9935433B9

Biological materials
Mutant
BKE10120 ([gene|762E7731EFEAC9F38074D7A7E9A3E5759437CDCA|hemE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10120 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTGATTTCCACCTTTCA,  downstream forward: _UP4_TAAGCATATCTTTTGGTATC
BKK10120 ([gene|762E7731EFEAC9F38074D7A7E9A3E5759437CDCA|hemE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10120 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTGATTTCCACCTTTCA,  downstream forward: _UP4_TAAGCATATCTTTTGGTATC
References
Reviews
28123057,37593721
Original Publications
17122346

762E7731EFEAC9F38074D7A7E9A3E5759437CDCA

Page visits: 1881

Time of last update: 2024-03-28 20:42:31

Author of last update: Jstuelk