gntK

gntK
168

gluconokinase

locus
BSU_40060
Molecular weight
57.00 kDa
pI
5.52
Protein length
Gene length
function
gluconate utilization
product
gluconokinase
essential
no
ec
2.7.1.12
synonyms
gntK

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1070 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,114,141  4,115,682
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The protein
Catalyzed reaction/ biological activity
ATP + D-gluconate --> 6-phospho-D-gluconate + ADP + H+ (according to UniProt)
Protein family
[wiki|FGGY kinase family] (according to UniProt)
Structure
[PDB|3GBT] (from ''Lactobacillus acidophilus'', 39% identity)
[AF|P12011]
Expression and Regulation
Operons
genes
[gene|1C566E54F8EF1A17A365FC49DFDA452AC5D0CA64|gntR]-[gene|72404FA6ECD62AEA3EFDB934DFB8DA581875605C|gntK]-[gene|C6810A4ACD51EB8D14E5B30163348058196266A1|gntP]-[gene|7E7187AA2DC172018A63A7B9CE48124F30311639|gntZ]
description
[pubmed|10746760,3020045]
regulation
induced by gluconate ([protein|search|GntR]) [Pubmed|3020045]
regulatory mechanism
[protein|1C566E54F8EF1A17A365FC49DFDA452AC5D0CA64|gntR]: repression, [Pubmed|3020045], in [regulon|protein:1C566E54F8EF1A17A365FC49DFDA452AC5D0CA64|gntR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|10666464], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: activation, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|3020045], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|1C566E54F8EF1A17A365FC49DFDA452AC5D0CA64|gntR]→[gene|7E7187AA2DC172018A63A7B9CE48124F30311639|gntZ]

2024-03-13 23:00:51

ghost

41

a4a9f34acee86d883fafe2368089737d1c13df10

02F8B40AEEBB8D4A2614150F30482A3F72134EF4

Biological materials
Mutant
BKE40060 ([gene|72404FA6ECD62AEA3EFDB934DFB8DA581875605C|gntK]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE40060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GCCGATATCGATTCCTAACA,  downstream forward: _UP4_TAGTACATGACATGAAGGGG
BKK40060 ([gene|72404FA6ECD62AEA3EFDB934DFB8DA581875605C|gntK]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK40060 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GCCGATATCGATTCCTAACA,  downstream forward: _UP4_TAGTACATGACATGAAGGGG
References
3011959,8288545,3037520,2537826,6322857,3020045,10746760,8370661,3020045,1659648,220817675

72404FA6ECD62AEA3EFDB934DFB8DA581875605C

Page visits: 2515

Time of last update: 2024-03-27 00:47:44

Author of last update: Melvin.boenninger