Glutamate metabolism

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Contents

Proteins involved in glutamate metabolism

Transport systems

Metabolic enzymes

Regulators

  • Key transcriptional regulators of nitrogen metabolism: GlnR, GltC, TnrA
  • Additional transcriptional regulators: AhrC, RocR, CcpA, Fur
  • Control of ammonium uptake: GlnK

Relevant SubtiWiki pages

Glutamate metabolism in SubtiPathways: Ammonium/ glutamate

Additional websites

Labs studying glutamate metabolism

Important publications

Reviews

Katrin Gunka, Fabian M Commichau
Control of glutamate homeostasis in Bacillus subtilis: a complex interplay between ammonium assimilation, glutamate biosynthesis and degradation.
Mol. Microbiol.: 2012, 85(2);213-24
[PubMed:22625175] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Jörg Stülke
Trigger enzymes: bifunctional proteins active in metabolism and in controlling gene expression.
Mol. Microbiol.: 2008, 67(4);692-702
[PubMed:18086213] [WorldCat.org] [DOI] (P p)

Abraham L Sonenshein
Control of key metabolic intersections in Bacillus subtilis.
Nat. Rev. Microbiol.: 2007, 5(12);917-27
[PubMed:17982469] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Karl Forchhammer, Jörg Stülke
Regulatory links between carbon and nitrogen metabolism.
Curr. Opin. Microbiol.: 2006, 9(2);167-72
[PubMed:16458044] [WorldCat.org] [DOI] (P p)

S H Fisher
Regulation of nitrogen metabolism in Bacillus subtilis: vive la différence!
Mol. Microbiol.: 1999, 32(2);223-32
[PubMed:10231480] [WorldCat.org] (P p)

Important original publications

Anne Krog, Tonje Marita Bjerkan Heggeset, Trond Erling Ellingsen, Trygve Brautaset
Functional characterization of key enzymes involved in L-glutamate synthesis and degradation in the thermotolerant and methylotrophic bacterium Bacillus methanolicus.
Appl. Environ. Microbiol.: 2013, 79(17);5321-8
[PubMed:23811508] [WorldCat.org] [DOI] (I p)

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