glcU

168

probable glucose uptake protein

locus: BSU_03920

Molecular weight: 30.74 kDa

pI: 10.67

Protein length: 287 aa

Gene length: 864 bp

function: unknown

product: unknown

essential: no

synonyms: glcU, ycxE

List of homologs in different organisms, belongs to COG4975 (Galperin et al., 2021)

Gene

Coordinates: 444,461 → 445,324

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The protein

Protein family

• GRP transporter (TC 2.A.7.5) family (single member, according to UniProt)

Structure

• [AF|P40420]

[wiki|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|AF5180DE23ADBBA4B58EC5D61A8C3EE08701E88B|glcU]-[gene|CA4597C6253CCF7D7954686A30AF041808BDF8E5|gdh]

  description: [Pubmed|3141376]

  regulation

  • expressed during sporulation ([protein|search|SigG], [wiki|SpoVT]) [Pubmed|3141376,8755877]

  regulatory mechanism

  • [protein|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]: repression, [Pubmed|8755877], in [regulon|protein:01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT regulon]

  sigma factors

  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|3141376], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]

Biological materials

Mutant

• MGNA-C016 (ycxE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2014 NBRP B. subtilis, Japan]
• BKE03920 (Δ[gene|AF5180DE23ADBBA4B58EC5D61A8C3EE08701E88B|glcU]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTTGGGGAACCTTCTT,  downstream forward: _UP4_TCATAACAAATGGAGGAGGA
• BKK03920 (Δ[gene|AF5180DE23ADBBA4B58EC5D61A8C3EE08701E88B|glcU]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03920 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTGTTGGGGAACCTTCTT,  downstream forward: _UP4_TCATAACAAATGGAGGAGGA

References

• 3141376,8755877,27766092,29512378