Genetic competence

Parent categories	4. Lifestyles 4.1. Exponential and early post-exponential lifestyles
Neighbouring categories	4.1.1. Motility and chemotaxis 4.1.2. Biofilm formation 4.1.3. Genetic competence
Related categories	ComA regulon ComK regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

Parent categories	3. Information processing 3.1. Genetics
Neighbouring categories	3.1.1. DNA replication 3.1.2. DNA condensation/ segregation 3.1.3. DNA restriction/ modification 3.1.4. DNA repair/ recombination 3.1.5. Genetic competence 3.1.6. Genetics/ other
Related categories	ComA regulon ComK regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

Labs working on genetic competence

• David Dubnau

Genes in this functional category

• addA
• addB
• bdbC
• bdbD
• coiA
• comA
• comC
• comEA
• comEB
• comEC
• comER
• comFA
• comFB
• comFC
• comGA
• comGB
• comGC
• comGD
• comGE
• comGF
• comGG
• comK
• comN
• comP
• comQ
• comS
• comX
• comZ
• dprA
• mecA
• med
• nin
• nucA
• oppA
• oppB
• oppC
• oppD
• oppF
• phrC
• phrF
• phrK
• pnpA
• radC
• rapC
• rapD
• rapF
• rapK
• recA
• rok
• sbcC
• sbcD
• yvcJ

Important reviews

Hongguang Xi, Lixia Duan, Marc Turcotte
Point-Cycle Bistability and Stochasticity in a Regulatory Circuit for Bacillus subtilis Competence.
Math Biosci: 2013;
[PubMed:23693123] [WorldCat.org] [DOI] (I a)

Lorena Espinar, Marta Dies, Tolga Cagatay, Gürol M Süel, Jordi Garcia-Ojalvo
Circuit-level input integration in bacterial gene regulation.
Proc. Natl. Acad. Sci. U.S.A.: 2013, 110(17);7091-6
[PubMed:23572583] [WorldCat.org] [DOI] (I p)

Suzy M Stiegelmeyer, Morgan C Giddings
Agent-based modeling of competence phenotype switching in Bacillus subtilis.
Theor Biol Med Model: 2013, 10(1);23
[PubMed:23551850] [WorldCat.org] [DOI] (I e)

Dawit Kidane, Silvia Ayora, Joann B Sweasy, Peter L Graumann, Juan C Alonso
The cell pole: the site of cross talk between the DNA uptake and genetic recombination machinery.
Crit. Rev. Biochem. Mol. Biol.: 2012, 47(6);531-55
[PubMed:23046409] [WorldCat.org] [DOI] (I p)

Anna Kuchina, Lorena Espinar, Tolga Çağatay, Alejandro O Balbin, Fang Zhang, Alma Alvarado, Jordi Garcia-Ojalvo, Gürol M Süel
Temporal competition between differentiation programs determines cell fate choice.
Mol. Syst. Biol.: 2011, 7;557
[PubMed:22146301] [WorldCat.org] [DOI] (I e)

Daniel Schultz, Peter G Wolynes, Eshel Ben Jacob, José N Onuchic
Deciding fate in adverse times: sporulation and competence in Bacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A.: 2009, 106(50);21027-34
[PubMed:19995980] [WorldCat.org] [DOI] (I p)

Jean-Pierre Claverys, Bernard Martin, Patrice Polard
The genetic transformation machinery: composition, localization, and mechanism.
FEMS Microbiol. Rev.: 2009, 33(3);643-56
[PubMed:19228200] [WorldCat.org] [DOI] (I p)

Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat. Rev. Microbiol.: 2004, 2(3);241-9
[PubMed:15083159] [WorldCat.org] [DOI] (P p)

Leendert W Hamoen, Gerard Venema, Oscar P Kuipers
Controlling competence in Bacillus subtilis: shared use of regulators.
Microbiology (Reading, Engl.): 2003, 149(Pt 1);9-17
[PubMed:12576575] [WorldCat.org] (P p)

P Tortosa, D Dubnau
Competence for transformation: a matter of taste.
Curr. Opin. Microbiol.: 1999, 2(6);588-92
[PubMed:10607621] [WorldCat.org] (P p)

D Dubnau
Binding and transport of transforming DNA by Bacillus subtilis: the role of type-IV pilin-like proteins--a review.
Gene: 1997, 192(1);191-8
[PubMed:9224890] [WorldCat.org] (P p)

D Dubnau
Genetic competence in Bacillus subtilis.
Microbiol. Rev.: 1991, 55(3);395-424
[PubMed:1943994] [WorldCat.org] (P p)