etfA

etfA
168

electron transfer flavoprotein (alpha subunit)

locus
BSU_28520
Molecular weight
34.39 kDa
pI
4.65
Protein length
Gene length
function
fatty acid degradation, calcium carbonate biomineralization
product
electron transfer flavoprotein (alpha subunit)
essential
no
synonyms
etfA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2025 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,915,365  2,916,342
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The protein
Protein family
ETF alpha-subunit/fixB family (single member, according to UniProt)
[wiki|Cofactors]
FAD (according to UniProt)
Structure
[PDB|1EFV] (the human protein, 39% identity) [pubmed|8962055]
[AF|P94551]
Expression and Regulation
Operons
genes
[gene|7AC5217CA35F8E134ABB35D74F1BA5E684D2E058|lcfA]-[gene|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]-[gene|3111ECB66CD3CFF0494AA3DF4D646102CF3B0FA8|fadB]-[gene|251600E5FD52DC0352A123F1224C037577F5A09C|etfB]-[gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]
description
[Pubmed|17189250]
regulation
induced by long chain acyl-CoA (C14 ... C20) ([protein|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]) [Pubmed|17189250]
regulatory mechanism
[protein|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]: repression, [Pubmed|17189250], in [regulon|protein:8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|21398533], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21398533], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Open in new tab

[gene|7AC5217CA35F8E134ABB35D74F1BA5E684D2E058|lcfA]→[gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]

2024-03-23 18:46:55

Jstuelk

62

d18d49394aac4cec0002a2695f8ea4b1c4cda4f5

DEE7D2778BB88C7028C79F5FEDED5CD757497033

genes
[gene|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]-[gene|3111ECB66CD3CFF0494AA3DF4D646102CF3B0FA8|fadB]-[gene|251600E5FD52DC0352A123F1224C037577F5A09C|etfB]-[gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]
description
[Pubmed|17189250]
regulation
induced by long-chain fatty acids ([protein|search|FadR]) [Pubmed|17189250]
Open in new tab

[gene|8A8F93BAD0582F712C9EE1C3FE6C04292E91F390|fadR]→[gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]

2024-03-23 17:41:44

ghost

58

079c8f1574d2e1a8270f558e4ec0295a90806447

FA5DAFE8C700F246311EFDCE5474D8DD396BEC38

Biological materials
Mutant
1A856 ( ''etfA''::''cat''), [Pubmed|17085570], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A856&Search=1A856 BGSC]
BKE28520 ([gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE28520 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCTAACATCCCCCTGTT,  downstream forward: _UP4_TAAAGGAAATCCCGGACTTT
BKK28520 ([gene|ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09|etfA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK28520 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTCTAACATCCCCCTGTT,  downstream forward: _UP4_TAAAGGAAATCCCGGACTTT
References
Reviews
17919287
Original Publications
17085570,17189250,20059546,21398533,8962055

ACA8FF923D72CC99F447E47F6A1381FEAD9DAB09

Page visits: 2426

Time of last update: 2024-03-29 08:53:34

Author of last update: Melvin.boenninger