csbX

168

general stress protein, putative 2-oxoglutarate permease

locus: BSU_27760

Molecular weight: 47.70 kDa

pI: 8.82

Protein length: 435 aa

Gene length: 1308 bp

function: unknown

product: putative 2-oxoglutarate permease

essential: no

synonyms: csbX

List of homologs in different organisms, belongs to COG2223 (Galperin et al., 2021)

Gene

Coordinates: 2,837,469  2,838,776

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The protein

Protein family

• [wiki|major facilitator superfamily] (according to UniProt)
• [wiki|Sugar transporter (TC 2.A.1.1) family] (according to UniProt)

Structure

• [AF|O05390]

Paralogous protein(s)

• [protein|FF60633F2902E4CA58B34FF3DAFF85B0D4007622|yoaB]

[wiki|Localization]

• forespore intermembrane space (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|12B260DBC4E29151364251837FD227593D0BF391|csbX]-[gene|A2C94BB9272407B305B90151F77835BB90414D0F|bofC]

  description: [Pubmed|9099855]

  regulation

  • expressed during sporulation in the forespore ([protein|search|SigF], [protein|search|SigG]) [Pubmed|16497325,9099855]

  regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|22900538], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]

  sigma factors

  • [protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, [Pubmed|15699190,9099855], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|9099855], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|11544224,9099855], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]

Biological materials

Mutant

• BKE27760 ([gene|12B260DBC4E29151364251837FD227593D0BF391|csbX]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTCCACCGCCTACT,  downstream forward: _UP4_TAGCCTCTTTGGTCAAACTA
• BKK27760 ([gene|12B260DBC4E29151364251837FD227593D0BF391|csbX]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27760 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTCCACCGCCTACT,  downstream forward: _UP4_TAGCCTCTTTGGTCAAACTA

References

• 9099855,22900538,11544224