CotU

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  • Description: spore coat protein

Gene name cotU
Synonyms ynzH
Essential no
Product spore coat protein
Function resistance of the spore
Gene expression levels in SubtiExpress: cotU
Interactions involving this protein in SubtInteract: CotU
MW, pI 11 kDa, 6.315
Gene length, protein length 258 bp, 86 aa
Immediate neighbours yncF, ynzJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YnzH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotU expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, GerR regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU17670

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol. Microbiol.: 2012, 83(2);245-60
[PubMed:22171814] [WorldCat.org] [DOI] (I p)

Giuseppina Cangiano, Antonio Mazzone, Loredana Baccigalupi, Rachele Isticato, Patrick Eichenberger, Maurilio De Felice, Ezio Ricca
Direct and indirect control of late sporulation genes by GerR of Bacillus subtilis.
J. Bacteriol.: 2010, 192(13);3406-13
[PubMed:20435725] [WorldCat.org] [DOI] (I p)

Rachele Isticato, Assunta Pelosi, Maurilio De Felice, Ezio Ricca
CotE binds to CotC and CotU and mediates their interaction during spore coat formation in Bacillus subtilis.
J. Bacteriol.: 2010, 192(4);949-54
[PubMed:20023017] [WorldCat.org] [DOI] (I p)

Rachele Isticato, Assunta Pelosi, Rita Zilhão, Loredana Baccigalupi, Adriano O Henriques, Maurilio De Felice, Ezio Ricca
CotC-CotU heterodimerization during assembly of the Bacillus subtilis spore coat.
J. Bacteriol.: 2008, 190(4);1267-75
[PubMed:18065538] [WorldCat.org] [DOI] (I p)

Erh-Min Lai, Nikhil D Phadke, Maureen T Kachman, Rebecca Giorno, Santiago Vazquez, Jenny A Vazquez, Janine R Maddock, Adam Driks
Proteomic analysis of the spore coats of Bacillus subtilis and Bacillus anthracis.
J. Bacteriol.: 2003, 185(4);1443-54
[PubMed:12562816] [WorldCat.org] [DOI] (P p)