Cell wall synthesis

Parent categories	1. Cellular processes 1.1. Cell wall and cell division
Neighbouring categories	1.1.1. Cell wall synthesis 1.1.2. Cell shape 1.1.3. Cell wall degradation/ turnover 1.1.4. Capsule biosynthesis and degradation 1.1.5. Cell wall/ other 1.1.6. Membrane dynamics 1.1.7. Cell division
Related categories	Cell shape Penicillin-binding proteins Cell wall biosynthetic complex Cell wall synthesis in SubtiPathways
Overview on the categories (Excel file) All genes and their categories (Excel file)

Cell wall synthesis is intimately linked to the determination of cell shape. The proteins involved in both functions interact in the cell wall biosynthetic complex.

Genes in this functional category

Biosynthesis of peptidoglycan

• alr
• dat
• ddl
• gcaD
• glmM
• glmS
• ldt
• mraY
• murAA
• murAB
• murB
• murC
• murD
• murE
• murF
• murG
• patA
• racE
• spoVB
• spoVE
• walJ
• yabM
• ykuQ
• ykuR
• yrpC
• ytgP

Biosynthesis of lipoteichoic acid

• dgkA
• dgkB
• ltaS
• yfnI
• yqgS
• yvgJ

Biosynthesis of teichoic acid

• dltA
• dltB
• dltC
• dltD
• dltE
• ggaA
• ggaB
• gtaB
• gtaC
• mnaA
• pgcA
• tagA
• tagB
• tagC
• tagD
• tagE
• tagF
• tagO

Biosynthesis of teichuronic acid

• tuaA/1
• tuaA/2
• tuaB
• tuaC
• tuaD
• tuaE
• tuaF
• tuaG
• tuaH

Penicillin-binding proteins

• dacA
• dacB
• dacC
• dacF
• pbpA
• pbpB
• pbpC
• pbpD
• pbpE
• pbpF
• pbpG
• pbpH
• pbpI
• pbpX
• ponA
• spoVD

Export of anionic polymers and attachment to peptidoglycan

• tagG
• tagH
• tagT
• tagU
• tagV

Biosynthesis of the carrier lipid undecaprenylphosphate

• bcrC
• uppS

Important Original Publications

Morgan Beeby, James C Gumbart, Benoît Roux, Grant J Jensen
Architecture and assembly of the Gram-positive cell wall.
Mol. Microbiol.: 2013, 88(4);664-72
[PubMed:23600697] [WorldCat.org] [DOI] (I p)

Siyuan Wang, Leon Furchtgott, Kerwyn Casey Huang, Joshua W Shaevitz
Helical insertion of peptidoglycan produces chiral ordering of the bacterial cell wall.
Proc. Natl. Acad. Sci. U.S.A.: 2012, 109(10);E595-604
[PubMed:22343529] [WorldCat.org] [DOI] (I p)

N V Potekhina, G M Streshinskaya, E M Tul'skaya, Yu I Kozlova, S N Senchenkova, A S Shashkov
Phosphate-containing cell wall polymers of bacilli.
Biochemistry Mosc.: 2011, 76(7);745-54
[PubMed:21999535] [WorldCat.org] [DOI] (I p)

Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745] [WorldCat.org] [DOI] (I p)

Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744] [WorldCat.org] [DOI] (I p)

Important Reviews

David L Popham
Visualizing the production and arrangement of peptidoglycan in Gram-positive cells.
Mol. Microbiol.: 2013, 88(4);645-9
[PubMed:23551458] [WorldCat.org] [DOI] (I p)

Nathalie T Reichmann, Angelika Gründling
Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes.
FEMS Microbiol. Lett.: 2011, 319(2);97-105
[PubMed:21388439] [WorldCat.org] [DOI] (I p)

Iain C Sutcliffe
Priming and elongation: dissection of the lipoteichoic acid biosynthetic pathway in Gram-positive bacteria.
Mol. Microbiol.: 2011, 79(3);553-6
[PubMed:21255102] [WorldCat.org] [DOI] (I p)

Waldemar Vollmer, Stephen J Seligman
Architecture of peptidoglycan: more data and more models.
Trends Microbiol.: 2010, 18(2);59-66
[PubMed:20060721] [WorldCat.org] [DOI] (I p)

Amit P Bhavsar, Eric D Brown
Cell wall assembly in Bacillus subtilis: how spirals and spaces challenge paradigms.
Mol. Microbiol.: 2006, 60(5);1077-90
[PubMed:16689786] [WorldCat.org] [DOI] (P p)

George C Stewart
Taking shape: control of bacterial cell wall biosynthesis.
Mol. Microbiol.: 2005, 57(5);1177-81
[PubMed:16101993] [WorldCat.org] [DOI] (P p)