bsdC

bsdC
168

phenolic acid decarboxylase

locus
BSU_03640
Molecular weight
52.86 kDa
pI
5.12
Protein length
Gene length
function
resistance to salicylic acid
product
phenolic acid decarboxylase
essential
no
synonyms
bsdC, yclC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0043 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
413,157 → 414,578
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The protein
Catalyzed reaction/ biological activity
conversion of vanillic acid to guaiacol [Pubmed|26658822]
4-hydroxybenzoate + H+ --> CO2 + phenol (according to UniProt)
4-hydroxy-3-methoxybenzoate + H+ --> CO2 + guaiacol (according to UniProt)
Protein family
ubiD family (single memberm, according to UniProt)
Structure
[PDB|5M1B] (from E. coli, 31% identity) [pubmed|28057757]
[AF|P94405]
Expression and Regulation
Operons
genes
[gene|8A83E44AFE9A1A635C65E6B526690AF7DA201BE1|bsdB]-[gene|FD23F4C2AFCBFE35A79116C5A707FACD454E4180|bsdC]-[gene|868DC9DE1C9C26C780F4CEAA4185640B5B6B781B|bsdD]
description
[Pubmed|17295427]
regulation
induced by salicylic acid ([protein|search|BsdA]) [Pubmed|17295427]
regulatory mechanism
[protein|28D03575FA24525C162E6C161631034568E89622|bsdA]: activation, [Pubmed|17295427], in [regulon|protein:28D03575FA24525C162E6C161631034568E89622|bsdA regulon]
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[gene|8A83E44AFE9A1A635C65E6B526690AF7DA201BE1|bsdB]→[gene|868DC9DE1C9C26C780F4CEAA4185640B5B6B781B|bsdD]

2024-01-24 02:15:34

ghost

38

9f1e53008322fc32f81f47f08c6a481f6a94f79a

5719B832927C879CFFE0ADDE90617DF8C801D919

Biological materials
Mutant
MGNA-C062 (yclC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2060 NBRP B. subtilis, Japan]
BKE03640 (Δ[gene|FD23F4C2AFCBFE35A79116C5A707FACD454E4180|bsdC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA,  downstream forward: _UP4_AATAAATAAGGAAAGGATGT
BKK03640 (Δ[gene|FD23F4C2AFCBFE35A79116C5A707FACD454E4180|bsdC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03640 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA,  downstream forward: _UP4_AATAAATAAGGAAAGGATGT
References
15979273,17295427,26658822,28057757

FD23F4C2AFCBFE35A79116C5A707FACD454E4180

Page visits: 2554

Time of last update: 2024-03-28 19:36:14

Author of last update: Melvin.boenninger