Difference between revisions of "YydF"

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[[Category:Protein-coding genes]]

Revision as of 14:09, 21 July 2009

  • Description: secreted peptide, controls LiaRS activity

Gene name yydF
Synonyms
Essential no
Product secreted peptide
Function control of LiaRS activity
MW, pI 5 kDa, 9.567
Gene length, protein length 147 bp, 49 aa
Immediate neighbours yydG, fbp
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YydF context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU40180

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: activated after transition to stationary phase(AbrB) PubMed
  • Regulatory mechanism: AbrB: transcription repression PubMed
  • Additional information:
    • the mRNA is very stable (half-life > 15 min) PubMed
    • the yydF portion of the mRNA belongs to the most stable mRNAs in B. subtilis PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Bronwyn G Butcher, Yi-Pin Lin, John D Helmann
The yydFGHIJ operon of Bacillus subtilis encodes a peptide that induces the LiaRS two-component system.
J Bacteriol: 2007, 189(23);8616-25
[PubMed:17921301] [WorldCat.org] [DOI] (I p)

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)