YydA

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  • Description: similar to pseudouridine methyltransferase

Gene name yydA
Synonyms
Essential no
Product similar to pseudouridine methyltransferase
Function may be involved in maturation of 23S rRNA
MW, pI 17 kDa, 9.314
Gene length, protein length 477 bp, 159 aa
Immediate neighbours yydB, yycS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YydA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

translation

This gene is a member of the following regulons

DnaA regulon

The gene

Basic information

  • Locus tag: BSU40230

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine (according to Swiss-Prot)
  • Protein family: RNA methyltransferase rlmH family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Rya Ero, Margus Leppik, Aivar Liiv, Jaanus Remme
Specificity and kinetics of 23S rRNA modification enzymes RlmH and RluD.
RNA: 2010, 16(11);2075-84
[PubMed:20817755] [WorldCat.org] [DOI] (I p)

Rya Ero, Lauri Peil, Aivar Liiv, Jaanus Remme
Identification of pseudouridine methyltransferase in Escherichia coli.
RNA: 2008, 14(10);2223-33
[PubMed:18755836] [WorldCat.org] [DOI] (I p)

Elzbieta Purta, Katarzyna H Kaminska, Joanna M Kasprzak, Janusz M Bujnicki, Stephen Douthwaite
YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.
RNA: 2008, 14(10);2234-44
[PubMed:18755835] [WorldCat.org] [DOI] (I p)

Shu Ishikawa, Yoshitoshi Ogura, Mika Yoshimura, Hajime Okumura, Eunha Cho, Yoshikazu Kawai, Ken Kurokawa, Taku Oshima, Naotake Ogasawara
Distribution of stable DnaA-binding sites on the Bacillus subtilis genome detected using a modified ChIP-chip method.
DNA Res: 2007, 14(4);155-68
[PubMed:17932079] [WorldCat.org] [DOI] (P p)