yydA

168

similar to pseudouridine methyltransferase

locus: BSU_40230

Molecular weight: 17.93 kDa

pI: 9.31

Protein length: 159 aa

Gene length: 480 bp

function: may be involved in maturation of 23S rRNA

product: similar to pseudouridine methyltransferase

essential: no

ec: null

synonyms: yydA

List of homologs in different organisms, belongs to COG1576 (Galperin et al., 2021)

Gene

Coordinates: 4,134,436  4,134,915

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The protein

Catalyzed reaction/ biological activity

• pseudouridine¹⁹¹⁵ in 23S rRNA + S-adenosyl-L-methionine --> H⁺ + N³-methylpseudouridine¹⁹¹⁵ in 23S rRNA + S-adenosyl-L-homocysteine (according to UniProt)

Protein family

• RNA methyltransferase rlmH family (single member, according to UniProt)

Structure

• [PDB|1TO0]
• [AF|Q45601]

Biological materials

Mutant

• MGNA-B814 (yydA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1813 NBRP B. subtilis, Japan]

References

• 17932079,18755836,18755835,20817755