Difference between revisions of "YxaM"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[resistance against toxins/ antibiotics]]}},
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{{SubtiWiki category|[[membrane proteins]]}}
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= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[AbrB regulon]]}},
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{{SubtiWiki regulon|[[CodY regulon]]}}
  
 
=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[resistance against toxins/ antibiotics]]}},
 
{{SubtiWiki category|[[membrane proteins]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 01:08, 9 December 2010

  • Description: similar to antibiotic resistance protein

Gene name yxaM
Synonyms
Essential no
Product unknown
Function unknown
Metabolic function and regulation of this protein in SubtiPathways:
Asp, Asn
MW, pI 44 kDa, 8.306
Gene length, protein length 1197 bp, 399 aa
Immediate neighbours asnH, yxaL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YxaM context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CodY regulon

The gene

Basic information

  • Locus tag: BSU39930

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: major facilitator superfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed during logrithmic growth (AbrB) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Mélanie A Hamon, Nicola R Stanley, Robert A Britton, Alan D Grossman, Beth A Lazazzera
Identification of AbrB-regulated genes involved in biofilm formation by Bacillus subtilis.
Mol Microbiol: 2004, 52(3);847-60
[PubMed:15101989] [WorldCat.org] [DOI] (P p)

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)

Ken-Ichi Yoshida, Izumi Ishio, Eishi Nagakawa, Yoshiyuki Yamamoto, Mami Yamamoto, Yasutaro Fujita
Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Microbiology (Reading): 2000, 146 ( Pt 3);573-579
[PubMed:10746760] [WorldCat.org] [DOI] (P p)

K Yoshida, Y Fujita, S D Ehrlich
Three asparagine synthetase genes of Bacillus subtilis.
J Bacteriol: 1999, 181(19);6081-91
[PubMed:10498721] [WorldCat.org] [DOI] (P p)