yxaA

yxaA
168

putative glycerate kinase

locus
BSU_40040
Molecular weight
39.24 kDa
pI
4.53
Protein length
Gene length
function
unknown
product
putative glycerate kinase
essential
no
ec
2.7.1.31
synonyms
yxaA, glxK

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1929 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,112,073  4,113,221
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The protein
Catalyzed reaction/ biological activity
(R)-glycerate + ATP --> 3-phospho-D-glycerate + ADP + H+ (according to UniProt)
Protein family
glycerate kinase type-1 family (single member, according to UniProt)
Structure
[PDB|3CWC] (from Salmonella Typhimurium 58% identity)
[AF|P42100]
Expression and Regulation
Operons
genes
[gene|4907D4585491349E2592B0EF9150312A80785EE5|yxaA]-[gene|9A223AE85131511B7EA3A71EA57D87E8B167FA67|yxaB]
description
[Pubmed|15805528,10746760]
regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|15805528,18326573], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|15805528], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
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[gene|4907D4585491349E2592B0EF9150312A80785EE5|yxaA]→[gene|9A223AE85131511B7EA3A71EA57D87E8B167FA67|yxaB]

2024-03-28 15:04:56

ghost

51

792b75318dc51d14509b206375aae633f110e1d3

6E63188162F8D54959B033216EA6A82BAA2419C1

Biological materials
Mutant
MGNA-B680 (yxaA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1679 NBRP B. subtilis, Japan]
BKE40040 ([gene|4907D4585491349E2592B0EF9150312A80785EE5|yxaA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE40040 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCAAATCGCCTCTTTCA,  downstream forward: _UP4_TAGCCGATGCACATGCCAAT
BKK40040 ([gene|4907D4585491349E2592B0EF9150312A80785EE5|yxaA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK40040 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCAAATCGCCTCTTTCA,  downstream forward: _UP4_TAGCCGATGCACATGCCAAT
References
10746760

4907D4585491349E2592B0EF9150312A80785EE5

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Time of last update: 2024-03-28 03:56:15

Author of last update: Melvin.boenninger