ywtE

ywtE
168

dephosphorylation of the riboflavin precursor, 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate (minor activity)

locus
BSU_35850
Molecular weight
31.44 kDa
pI
4.76
Protein length
Gene length
function
dephosphorylation of the riboflavin precursor, 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate (minor activity)
product
unknown
essential
no
ec
3.1.3.-
synonyms
ywtE

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0561 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,695,363  3,696,223
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The protein
Catalyzed reaction/ biological activity
dephosphorylation of the riboflavin precursor, 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate [Pubmed|26316208]
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O --> 5-amino-6-(D-ribitylamino)uracil + phosphate (according to UniProt)
Protein family
[wiki|HAD superfamily] (according to UniProt)  [Pubmed|26316208]
[wiki|Cof family] (according to UniProt)
Structure
[PDB|1NRW] ([protein|AF9523D3AA3C032B70175BCFFED34E9A42ED01AF|phoC], 39% identity)
[AF|P96741]
Expression and Regulation
Operons
genes
[gene|9730F7C18AC7CA68D144717851A0C261D9647E31|ywtE]
description
[Pubmed|22383849]
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[gene|9730F7C18AC7CA68D144717851A0C261D9647E31|ywtE]

2024-03-20 03:42:39

Jstuelk

53

3780baca35dd1a6c92f6c8f766e07c702b82fca9

08836DB6FA16F97B125DDCCA25A3CB705756A28D

genes
[gene|68FE85BAA457199D34C9068F38756972CD2D280D|tagT]-[gene|9730F7C18AC7CA68D144717851A0C261D9647E31|ywtE]
description
[Pubmed|22383849]
regulation
expressed at high salt concentrations ([protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]) [pubmed|18179421]
sigma factors
[protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM]: sigma factor, [Pubmed|18179421], in [regulon|protein:081DF3EE9FA56209D648C7677188C61CE3AA8E41|sigM regulon]
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[gene|68FE85BAA457199D34C9068F38756972CD2D280D|tagT]→[gene|9730F7C18AC7CA68D144717851A0C261D9647E31|ywtE]

2024-03-23 01:44:08

Jstuelk

71

23d9afb7d569bc46f4d89a080f32c0434f248bde

E687E4D92945FDEC837B783F745A0A7206B4A05E

Biological materials
Mutant
MGNA-A546 (ywtE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/546 NBRP B. subtilis, Japan]
BKE35850 ([gene|9730F7C18AC7CA68D144717851A0C261D9647E31|ywtE]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE35850 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGTAGGGGAACCTCCT,  downstream forward: _UP4_TAAAGAAAAGACTCCAGAGA
BKK35850 ([gene|9730F7C18AC7CA68D144717851A0C261D9647E31|ywtE]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK35850 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATGTAGGGGAACCTCCT,  downstream forward: _UP4_TAAAGAAAAGACTCCAGAGA
References
26316208

9730F7C18AC7CA68D144717851A0C261D9647E31

Page visits: 2101

Time of last update: 2024-03-27 22:38:17

Author of last update: Melvin.boenninger