Difference between revisions of "YwpB"

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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''fabZ''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''fabZ''
 
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes {{PubMed|23109554}}
 
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|style="background:#ABCDEF;" align="center"| '''Product''' || β-hydroxyacyl-ACP dehydratase  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || β-hydroxyacyl-ACP dehydratase  
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[biosynthesis of lipids]]}}
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{{SubtiWiki category|[[biosynthesis of lipids]]}},
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{{SubtiWiki category|[[essential genes]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 
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* essential {{PubMed|23109554}}
 
=== Database entries ===
 
=== Database entries ===
  
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=References=
 
=References=
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'''Additional publications:''' {{PubMed|23109554}}
 
<pubmed>17919287 19280690 </pubmed>
 
<pubmed>17919287 19280690 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 13:11, 31 October 2012

  • Description: β-hydroxyacyl-(acyl carrier protein) dehydratase

Gene name ywpB
Synonyms fabZ
Essential yes PubMed
Product β-hydroxyacyl-ACP dehydratase
Function fatty acid biosynthesis
Gene expression levels in SubtiExpress: ywpB
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 14 kDa, 9.36
Gene length, protein length 396 bp, 132 aa
Immediate neighbours mscL, rapD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwpB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YwpB expression.png















Categories containing this gene/protein

biosynthesis of lipids, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU36370

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: FabZ subfamily (according to Swiss-Prot)
  • Paralogous protein(s): YcsD

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 3D6X (from Campylobacter jejuni, 45% identity, 67% similarity) PubMed
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Andrew S Kirkpatrick, Takeshi Yokoyama, Kyoung-Jae Choi, Hye-Jeong Yeo
Campylobacter jejuni fatty acid synthase II: structural and functional analysis of beta-hydroxyacyl-ACP dehydratase (FabZ).
Biochem Biophys Res Commun: 2009, 380(2);407-12
[PubMed:19280690] [WorldCat.org] [DOI] (I p)

Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287] [WorldCat.org] [DOI] (P p)