Difference between revisions of "YwpB"
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''fabZ'' | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''fabZ'' | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || | + | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes {{PubMed|23109554}} |
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|style="background:#ABCDEF;" align="center"| '''Product''' || β-hydroxyacyl-ACP dehydratase | |style="background:#ABCDEF;" align="center"| '''Product''' || β-hydroxyacyl-ACP dehydratase | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
| − | + | <br/><br/> | |
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[biosynthesis of lipids]]}} | + | {{SubtiWiki category|[[biosynthesis of lipids]]}}, |
| + | {{SubtiWiki category|[[essential genes]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | * essential {{PubMed|23109554}} | |
=== Database entries === | === Database entries === | ||
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=References= | =References= | ||
| + | '''Additional publications:''' {{PubMed|23109554}} | ||
<pubmed>17919287 19280690 </pubmed> | <pubmed>17919287 19280690 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:11, 31 October 2012
- Description: β-hydroxyacyl-(acyl carrier protein) dehydratase
| Gene name | ywpB |
| Synonyms | fabZ |
| Essential | yes PubMed |
| Product | β-hydroxyacyl-ACP dehydratase |
| Function | fatty acid biosynthesis |
| Gene expression levels in SubtiExpress: ywpB | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
| MW, pI | 14 kDa, 9.36 |
| Gene length, protein length | 396 bp, 132 aa |
| Immediate neighbours | mscL, rapD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of lipids, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU36370
Phenotypes of a mutant
- essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: FabZ subfamily (according to Swiss-Prot)
- Paralogous protein(s): YcsD
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P94584
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Andrew S Kirkpatrick, Takeshi Yokoyama, Kyoung-Jae Choi, Hye-Jeong Yeo
Campylobacter jejuni fatty acid synthase II: structural and functional analysis of beta-hydroxyacyl-ACP dehydratase (FabZ).
Biochem Biophys Res Commun: 2009, 380(2);407-12
[PubMed:19280690]
[WorldCat.org]
[DOI]
(I p)
Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287]
[WorldCat.org]
[DOI]
(P p)
