YwcA

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  • Description: similar to Na+-dependent symport

Gene name ywcA
Synonyms ipa-31r
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: ywcA
Metabolic function and regulation of this protein in SubtiPathways:
YwcA
MW, pI 54 kDa, 7.201
Gene length, protein length 1548 bp, 516 aa
Immediate neighbours ywcB, ywbO
Sequences Protein DNA DNA_with_flanks
Genetic context
YwcA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YwcA expression.png















Categories containing this gene/protein

transporters/ other, membrane proteins, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

  • Locus tag: BSU38240

Phenotypes of a mutant

    • ywcBA mutant has slightly reduced acetic acid transport PubMed
    • ywcBA mutant shows earlier pellicle biofilm formation PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • the protein is involved in acetate transport PubMed
    • the protein is not involved in proline transport PubMed
  • Protein family: solute:sodium symporter family (SSS family)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during sporulation (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Adrienne Zaprasis, Tamara Hoffmann, Lorena Stannek, Katrin Gunka, Fabian M Commichau, Erhard Bremer
The γ-aminobutyrate permease GabP serves as the third proline transporter of Bacillus subtilis.
J Bacteriol: 2014, 196(3);515-26
[PubMed:24142252] [WorldCat.org] [DOI] (I p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)