ywaD

ywaD
168

double-zinc aminopeptidase

locus
BSU_38470
Molecular weight
49.29 kDa
pI
6.64
Protein length
Gene length
function
unknown
product
double-zinc aminopeptidase
essential
no
synonyms
ywaD, ipa-8r

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2234 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,948,555  3,949,922
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The protein
Catalyzed reaction/ biological activity
Release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys (according to UniProt)
Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids (according to UniProt)
Protein family
peptidase M28 family (single member, according to UniProt)
Structure
[PDB|6HC6]
[PDB|6HC7]
[AF|P25152]
[wiki|Localization]
extracellular (signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
genes
[gene|162B960244B0E1334F9E99E7E0F050D3312830E5|ywaD]
description
[Pubmed|9353933]
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[gene|162B960244B0E1334F9E99E7E0F050D3312830E5|ywaD]

2024-03-27 22:04:15

ghost

34

d7e26ec189089184a08ea54c314a273da886d187

DF22B853719D049D28EA143A9EC77622D8439210

Biological materials
Mutant
MGNA-B678 (ywaD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1677 NBRP B. subtilis, Japan]
BKE38470 ([gene|162B960244B0E1334F9E99E7E0F050D3312830E5|ywaD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38470 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAAAAATAAACCTCCCC,  downstream forward: _UP4_TAAAAAAAGACGGCACTTGG
BKK38470 ([gene|162B960244B0E1334F9E99E7E0F050D3312830E5|ywaD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38470 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAAAAATAAACCTCCCC,  downstream forward: _UP4_TAAAAAAAGACGGCACTTGG
References
15668014,23426795,18957862,23787698,24633010,26898926,28257579

162B960244B0E1334F9E99E7E0F050D3312830E5

Page visits: 2959

Time of last update: 2024-03-28 20:05:40

Author of last update: Mparker