YwaD

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  • Description: double-zinc aminopeptidase

Gene name ywaD
Synonyms ipa-8r
Essential no
Product double-zinc aminopeptidase
Function unknown
Gene expression levels in SubtiExpress: ywaD
MW, pI 49 kDa, 6.638
Gene length, protein length 1365 bp, 455 aa
Immediate neighbours tyrZ, ywaC
Sequences Protein DNA DNA_with_flanks
Genetic context
YwaD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YwaD expression.png















Categories containing this gene/protein

poorly characterized/ putative enzymes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU38470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: M28B subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Xinxing Gao, Wenjing Cui, Ning Ding, Zhongmei Liu, Yaping Tian, Zhemin Zhou
Structure-based approach to alter the substrate specificity of Bacillus subtilis aminopeptidase.
Prion: 2013, 7(4);328-34
[PubMed:23787698] [WorldCat.org] [DOI] (I p)

Xinxing Gao, Wenjing Cui, Yaping Tian, Zhemin Zhou
Over-expression, secretion, biochemical characterisation, and structure analysis of Bacillus subtilis aminopeptidase.
J Sci Food Agric: 2013, 93(11);2810-5
[PubMed:23426795] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Yifat Fundoiano-Hershcovitz, Larisa Rabinovitch, Smadar Shulami, Vera Reiland, Gil Shoham, Yuval Shoham
The ywad gene from Bacillus subtilis encodes a double-zinc aminopeptidase.
FEMS Microbiol Lett: 2005, 243(1);157-63
[PubMed:15668014] [WorldCat.org] [DOI] (P p)