YvrL

• Description: anti-Sig(YvrI-YvrHa)
  
  

Gene name	yvrL
Synonyms
Essential	no
Product	anti-Sig(YvrI-YvrHa)
Function	control of Sig(YvrI-YvrHa) activity
MW, pI	15 kDa, 9.427
Gene length, protein length	408 bp, 136 aa
Immediate neighbours	oxdC, yvrN
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33250

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34686

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: oxdC-yvrL PubMed

• [[Sigma factor]]: YvrI-YvrH PubMed

• Regulation: induced by acidic growth conditions PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: TMB043 (erm), available in the Thorsten Mascher lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

References

Shawn R MacLellan, John D Helmann, Haike Antelmann
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
J Bacteriol: 2009, 191(3);931-9
[PubMed:19047353] [WorldCat.org] [DOI] (I p)

Shawn R MacLellan, Tina Wecke, John D Helmann
A previously unidentified sigma factor and two accessory proteins regulate oxalate decarboxylase expression in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);954-67
[PubMed:18573182] [WorldCat.org] [DOI] (I p)