YvrHb

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Revision as of 19:25, 30 November 2009 by Jstuelk (talk | contribs) (Extended information on the protein)
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Gene name yvrHb
Synonyms yvrH
Essential no
Product two-component response regulator
Function regulation cell surface maintenance
MW, pI 26.6 kDa, 5.23
Gene length, protein length 714 bp, 237 amino acids
Immediate neighbours yvrHa, yvrG
Gene sequence (+200bp) Protein sequence
Genetic context
YvrHa yvrHb context.GIF



The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

unusual autolysis and higher susceptibility to cell envelope antibiotics (bacitracin, aztreonam, cefepime, fosfomycin) PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: no entry

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription activator PubMed
  • Protein family: OmpR family
  • Paralogous protein(s):

The YvrHb regulon

subject to positive control: dltA-dltB-dltC-dltD-dltE, sigX-rsiX, sunA, sunT-bdbA-yolJ-bdbB, wapA-yxxG, wprA, yvrI-yvrHa PubMed

subject to negative control: lytA-lytB-lytC PubMed

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation (Asp) by YvrG PubMed
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [1]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References