yvcN

yvcN
168

unknown

locus
BSU_34730
Molecular weight
28.68 kDa
pI
5.58
Protein length
Gene length
function
unknown
product
unknown
essential
no
synonyms
yvcN

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2162 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,568,527 → 3,569,291
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The protein
Protein family
[wiki|Acetyltransferase family] (according to UniProt)
Structure
[PDB|3LNB] (from ''B. anthracis'', 35% identity, 68% similarity)
[AF|O06977]
Additional information
The gene is annotated in KEGG as an ortholog of EC 2.3.1.5 and is marked in Swiss-Prot as “uncharacterized acetyltransferase” (EC 2.3.1.-). No EC annotation is available in MetaCyc.No literature/ experimental evidence supporting the annotation is available.  [Pubmed|19935659]
Expression and Regulation
Operons
genes
[gene|0C40455EB53D25363FC3EB0E84502A76520F5F91|nahA]-[gene|EB12C6B4F36B57BF0C59CE048CBAE18734C78D35|yvcJ]-[gene|7150BABA5086D5E2EB8102E4901A216F43576282|glmR]-[gene|1986DB3078FBA16D6ACCD70EEAC95C46564D0958|whiA]-[gene|A269774F2FDC94F93BA5F1360FFFE754B50383AD|crh]-[gene|C521BEE1EEEA7AD283A3C47C34301A8603CD9188|yvcN]
description
[Pubmed|9237995]
regulation
constitutive expression at both protein and RNA levels [Pubmed|24097947,22383849]
expression
in Enterococcus faecalis: induced upon cell wall stress (vancomycin) ([protein|1986DB3078FBA16D6ACCD70EEAC95C46564D0958|whiA]) [pubmed|38512984]
regulatory mechanism
[protein|1986DB3078FBA16D6ACCD70EEAC95C46564D0958|whiA]: transcription repression, described for Enterococcus faecalis [pubmed|38512984], in [regulon|protein:1986DB3078FBA16D6ACCD70EEAC95C46564D0958|whiA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|16272399], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
A [protein|search|ncRNA] is predicted between '[protein|search|yvcI]' and '[protein|1BC439BBCD5FE19D5780519D7E4317C2EFF0D21B|trxB]' [PubMed|20525796]
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[gene|0C40455EB53D25363FC3EB0E84502A76520F5F91|nahA]→[gene|C521BEE1EEEA7AD283A3C47C34301A8603CD9188|yvcN]

2024-03-22 09:41:40

Jstuelk

98

BCC5699F6256B8A1B7FD8A979DBBBC9D4D1198AB

9244FB113E998572106D983A19AB3AC81B9F9D35

Biological materials
Mutant
MGNA-B638 (yvcN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1637 NBRP B. subtilis, Japan]
BKE34730 (Δ[gene|C521BEE1EEEA7AD283A3C47C34301A8603CD9188|yvcN]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TAGAAAGTCACTCATTTTTA,  downstream forward: _UP4_TAACGTGAAAAGCTTGCAGG
BKK34730 (Δ[gene|C521BEE1EEEA7AD283A3C47C34301A8603CD9188|yvcN]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TAGAAAGTCACTCATTTTTA,  downstream forward: _UP4_TAACGTGAAAAGCTTGCAGG
two-hybrid system
''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([wiki|BACTH]), available in [wiki|Jörg Stülke]'s lab
References
9237995,16272399

C521BEE1EEEA7AD283A3C47C34301A8603CD9188

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Time of last update: 2024-03-29 08:33:28

Author of last update: Jstuelk