frlP

168

aminosugar [wiki|ABC transporter] (ATP-binding protein)

locus: BSU_32550

Molecular weight: 41.19 kDa

pI: 6.07

Protein length: 367 aa

Gene length: 1104 bp

function: uptake of sugar amines

product: aminosugar [wiki|ABC transporter] (ATP-binding protein)

essential: no

synonyms: yurJ

List of homologs in different organisms, belongs to COG3839 (Galperin et al., 2021)

Gene

Coordinates: 3,345,013  3,346,116

Advertisement

The protein

Protein family

• [wiki|ABC transporter superfamily] (according to UniProt)

[wiki|Domains]

• [wiki|ABC transporter domain] (aa 4-234) (according to UniProt)

Structure

• [PDB|1G29] (from Thermococcus litoralis, 50% identity) [pubmed|11080142]
• [AF|O32151]

Modification

• phosphorylated on Ser-3 [Pubmed|20509597]

Paralogous protein(s)

• [protein|434F6C546F783503A82D390FD238F05025FC1802|msmX]

[wiki|Localization]

• membrane associated (via [protein|1F245030D0C81DC96FC0642199CA00579CF46D06|frlM]-[protein|8256CAAEC591E40A8CB172FF053E03BFFD5A4B54|frlN]) [Pubmed|10092453,18763711]

Biological materials

Mutant

• MGNA-A556 (yurJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/556 NBRP B. subtilis, Japan]
• BKE32550 ([gene|3B9331D6755B8253944AB33521BBF2B3EBA4CAEB|frlP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAGAAAAGTCCCCCTAT,  downstream forward: _UP4_TAGAAAAAGGTGCTCCTCAA
• BKK32550 ([gene|3B9331D6755B8253944AB33521BBF2B3EBA4CAEB|frlP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32550 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCAGAAAAGTCCCCCTAT,  downstream forward: _UP4_TAGAAAAAGGTGCTCCTCAA

References

• 12618455,10092453,18763711,20509597,11080142,33177617