Difference between revisions of "YugI"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31390&redirect=T BSU31390]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yugI.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yugI.html]
Line 88: Line 89:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU31390&redirect=T BSU31390]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2K4K 2K4K]
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2K4K 2K4K]

Revision as of 14:37, 2 April 2014

  • Description: similar to a domain of E. coli polyribonucleotide phosphorylase and to four repeated domains at the N-terminus of E. coli ribosomal protein S1, has an RNA-binding surface

Gene name yugI
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yugI
MW, pI 14 kDa, 5.918
Gene length, protein length 390 bp, 130 aa
Immediate neighbours yuzA, alaT
Sequences Protein DNA DNA_with_flanks
Genetic context
YugI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YugI expression.png















Categories containing this gene/protein

proteins of unknown function, most abundant proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU31390

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Wenyu Yu, Bingke Yu, Jicheng Hu, Wei Xia, Changwen Jin, Bin Xia
1H, 13C, and 15N resonance assignments of a general stress protein GSP13 from Bacillus subtilis.
Biomol NMR Assign: 2008, 2(2);163-5
[PubMed:19636895] [WorldCat.org] [DOI] (I p)

Wenyu Yu, Jicheng Hu, Bingke Yu, Wei Xia, Changwen Jin, Bin Xia
Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins.
J Biomol NMR: 2009, 43(4);255-9
[PubMed:19152054] [WorldCat.org] [DOI] (I p)

Ulf Gerth, Holger Kock, Ilja Kusters, Stephan Michalik, Robert L Switzer, Michael Hecker
Clp-dependent proteolysis down-regulates central metabolic pathways in glucose-starved Bacillus subtilis.
J Bacteriol: 2008, 190(1);321-31
[PubMed:17981983] [WorldCat.org] [DOI] (I p)

Christine Eymann, Annette Dreisbach, Dirk Albrecht, Jörg Bernhardt, Dörte Becher, Sandy Gentner, Le Thi Tam, Knut Büttner, Gerrit Buurman, Christian Scharf, Simone Venz, Uwe Völker, Michael Hecker
A comprehensive proteome map of growing Bacillus subtilis cells.
Proteomics: 2004, 4(10);2849-76
[PubMed:15378759] [WorldCat.org] [DOI] (P p)

Christine Eymann, Georg Homuth, Christian Scharf, Michael Hecker
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.
J Bacteriol: 2002, 184(9);2500-20
[PubMed:11948165] [WorldCat.org] [DOI] (P p)

Bauke Oudega, Gregory Koningstein, Luísa Rodrigues, Maria de Sales Ramon, Helmut Hilbert, Andreas Düsterhöft, Thomas M Pohl, Thomas Weitzenegger
Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai).
Microbiology (Reading): 1997, 143 ( Pt 8);2769-2774
[PubMed:9274030] [WorldCat.org] [DOI] (P p)