Difference between revisions of "YtxJ"

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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU29760 ytxJ]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 5.089   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 12 kDa, 5.089   

Revision as of 15:01, 7 August 2012

  • Description: general stress protein

Gene name ytxJ
Synonyms csb40
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: ytxJ
MW, pI 12 kDa, 5.089
Gene length, protein length 324 bp, 108 aa
Immediate neighbours aroA, ytxH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtxJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtxJ expression.png
























Categories containing this gene/protein

general stress proteins (controlled by SigB), phosphoproteins

This gene is a member of the following regulons

SigB regulon, SigH regulon

The gene

Basic information

  • Locus tag: BSU29760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: Trx family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: contains a single conserved Cys residue in a motif (TCPIS) reminiscent of that found in monothiol glutaredoxins [3]
  • Modification: phosphorylation on (Thr-93 OR Ser-94 OR Ser-96 OR Thr-99) PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [4]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

YpdA, YqiW, YphP and YtxJ cooccur in those species predicted to synthesize bacillithiol.

References

Ahmed Gaballa, Gerald L Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C Fahey, John D Helmann
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
Proc Natl Acad Sci U S A: 2010, 107(14);6482-6
[PubMed:20308541] [WorldCat.org] [DOI] (I p)

Boris Macek, Ivan Mijakovic, Jesper V Olsen, Florian Gnad, Chanchal Kumar, Peter R Jensen, Matthias Mann
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Mol Cell Proteomics: 2007, 6(4);697-707
[PubMed:17218307] [WorldCat.org] [DOI] (P p)

A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224] [WorldCat.org] [DOI] (P p)

D Varón, M S Brody, C W Price
Bacillus subtilis operon under the dual control of the general stress transcription factor sigma B and the sporulation transcription factor sigma H.
Mol Microbiol: 1996, 20(2);339-50
[PubMed:8733232] [WorldCat.org] [DOI] (P p)