Difference between revisions of "YtpQ"

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Revision as of 14:20, 16 May 2013

  • Description: unknown

Gene name ytpQ
Synonyms
Essential no
Product unknown
Function maybe involved in iron homeostasis
Gene expression levels in SubtiExpress: ytpQ
MW, pI 30 kDa, 5.3
Gene length, protein length 807 bp, 269 aa
Immediate neighbours ytpR, ytpP
Sequences Protein DNA DNA_with_flanks
Genetic context
YtpQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtpQ expression.png















Categories containing this gene/protein

acquisition of iron, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

  • Locus tag: BSU29830

Phenotypes of a mutant

  • derepression of the Fur and PerR regulons PubMed
  • elevated oxidative protein damage upon exposure of the cells to methylglyoxal PubMed
  • the spx ytpQ doulbe mutant shows reduced growth in minimal medium and hypersensitivity to methylglyoxal PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0354 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Peter Zuber, Shefali Chauhan, Praseeda Pilaka, Michiko M Nakano, Sairam Gurumoorthy, Ann A Lin, Skye M Barendt, Bui Khanh Chi, Haike Antelmann, Ulrike Mäder
Phenotype enhancement screen of a regulatory spx mutant unveils a role for the ytpQ gene in the control of iron homeostasis.
PLoS One: 2011, 6(9);e25066
[PubMed:21949854] [WorldCat.org] [DOI] (I p)