YtdI

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  • Description: inorganic polyphosphate/ATP-NAD kinase

Gene name ytdI
Synonyms ppnKB
Essential no
Product inorganic polyphosphate/ATP-NAD kinase
Function generation of NADP from NAD
Gene expression levels in SubtiExpress: ytdI
MW, pI 30 kDa, 6.49
Gene length, protein length 801 bp, 267 aa
Immediate neighbours sppA, ytcJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YtdI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtdI expression.png
























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29540

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + NAD+ = ADP + NADP+ (according to Swiss-Prot)
  • Protein family: NAD kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1YT5 (from Thermotoga maritima) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947

Vaheh Oganesyan, Candice Huang, Paul D Adams, Jaru Jancarik, Hisao A Yokota, Rosalind Kim, Sung-Hou Kim
Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2005, 61(Pt 7);640-6
[PubMed:16511117] [WorldCat.org] [DOI] (I p)